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Post by Admin on Nov 18, 2019 16:15:13 GMT
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Post by Admin on Jan 25, 2020 13:39:24 GMT
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Post by Admin on Jul 9, 2020 13:40:10 GMT
Moore et al. studied 1527 cases of violence reported for 31 drugs. They concluded, “Acts of violence towards others were a genuine and serious adverse drug event associated with a relatively small group of drugs”.22 Varenicline, a drug for smoking cessation, was followed by antidepressants, with fluoxetine and paroxetine having the highest ranking. Violence associated with venlafaxine and desvenlafaxine, a drug and its first metabolite, make that pair the most implicated in violence, which can manifest as suicide and/or on others, as homicide. This confirmed the finding of Barbui et al.23 In the drugs companies' own trials presented for their licensing, “new generation” or “atypical” antipsychotics were found to carry double the risk of suicide on antidepressants.24 The relevance of cytochrome P450 polymorphism in forensic medicine and akathisia-related violence and suicide www.sciencedirect.com/science/article/pii/S1752928X16300051Abstract Adverse drug reactions and interactions are among the major causes of death in the United States. Antidepressants have been reported as causing suicide and homicide and share the class attribute of frequently producing akathisia, a state of severe restlessness associated with thoughts of death and violence. Medical examiners can now identify some pharmacogenetic interactions that cause drugs, deemed safe for most, to be lethal to others. Such deaths do not yet include medication-induced, akathisia-related suicides and homicides. An extrapyramidal side effect, akathisia is a manifestation of drug toxicity whose causes lie, inter alia, in drugs, doses, and co-prescribed medications that inhibit and compete for metabolizing enzymes, which may themselves be defective. In this paper, we report our investigation into adverse drug reactions/interactions in three persons who committed homicide, two also intending suicide, while on antidepressants prescribed for stressful life events. Their histories of medication use, adverse reactions and reasons for changes in medications are presented. DNA samples were screened for variants in the cytochrome P450 gene family; that produce drug metabolizing enzymes. All three cases exhibit genotype-based diminished metabolic capability that, in combination with their enzyme inhibiting/competing medications, decreased metabolism further and are the likely cause of these catastrophic events.
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Post by Admin on Feb 14, 2021 0:10:42 GMT
New interview with Jill Nickens, president and founder of the Akathisia Alliance for Education and Research, a nonprofit organization formed by people who have personal experience of akathisia. The group includes biochemists, psychologists, nurses, attorneys, business owners, and others who have survived akathisia, suicidality and devastating personal losses due, in part, to a lack of awareness by medical professionals. They have come together to inform and raise awareness to help minimize the risk of developing akathisia. Jill Nickens – The Akathisia Alliance for Education and ResearchBy James Moore -February 13, 2021 www.madinamerica.com/2021/02/jill-nickens-akathisia-alliance-education-research/akathisiaalliance.org/for-patients/
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Post by Admin on Nov 24, 2023 11:57:39 GMT
For Clinicians This page includes vital information about akathisia that cannot be found in medical journals such as tips for diagnosing akathisia, reasons it is often misdiagnosed as a functional neurological disorder, and about its dangerous subjective symptoms that can only be understood by those who have experienced it. It also contains evidence of akathisia's link to suicide, homicide, and mass shootings with full-text PDFs and excerpts from peer-reviewed literature with references for additional reading. Thank you for your interest in learning more about akathisia from the Akathisia Alliance for Education and Research nonprofit organization. We have 450+ members, including physicians, scientists, nurses, college professors, and many others from all walks of life who have experienced akathisia and are working together to help prevent others from suffering as we did. akathisiaalliance.org/for-clinicians/
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Post by Admin on Nov 24, 2023 21:15:41 GMT
Akathisia Jason Patel; Raman Marwaha. www.ncbi.nlm.nih.gov/books/NBK519543/Continuing Education Activity Akathisia is a neuropsychiatric syndrome that can occur as an adverse effect of antipsychotic medications and manifests as psychomotor restlessness. In recent years, akathisia has additionally been found to occur in certain individuals as an adverse effect of with calcium channel blockers, antiemetics, anti-vertigo drugs, cocaine, and sedatives used in anesthesia. This activity reviews the evaluation and management of akathisia and highlights the role of the interprofessional team in the recognition and management of this condition. Objectives: Review the pathophysiologic basis of akathisia. Outline the expected history and physical findings for a patient with akathisia. Identify the treatment options available for akathisia. Explain the interprofessional team strategies for improving care coordination and communication for patients with akathisia.
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Post by Admin on Feb 7, 2024 20:00:42 GMT
Joey Marino, actor dies: Tardive Dyskinesia beyondmeds.com/2024/02/07/joey-marino-actor-dies-tardive-dyskinesia/Joey Marino died recently. I have tardive dyskinesia too. People do not understand how serious it is. Life is nightmarish and we plug along doing the best we can. No one wants to know ugly so we try to dwell on other things when we are with people….because everyone disappears around serious illness. Especially when it’s not legitimized in ways like cancer or some other diseases are. Have a weird chronic illness and be ostracized. They call them invisible diseases. They are invisible because no one wants to see. Joey plugged along a long time and so am I. This is devastating. No one understands how awful TD is. Learn and help and prevent this for others please. I’ve written quite a lot on what I understand about it. Visit my sites or Mad in America to read that stuff if you’re interested. Let’s not let Joey Marino die in vain. Learn about what you do not know. from Mad in America:
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